CES 2023 in Las Vegas

CES 2023 in Las Vegas

Cysmic joined the 2023 Consumer Electronics Show (CES) – the most influential tech event in the world. CES took place in Las Vegas, NV, from January 5th to 8th, 2023, proving ground for breakthrough technologies and global innovators.

Prior to the main event, the Cysmic delegation participated in the Silicon Valley Funding Summit – a networking and pitching event hosted by European Commission’s ENRICH in the USA initiative and Angel Launch to connect multi-million dollar investors to global startups for funding and deal-making. Dr. Steffen M. Recktenwald pitched on behalf of Cysmic at the funding summit. The jury selected Cysmic and its pitch as one of the top four of the event.

During CES, Cysmic joined myGlobalVillage – an international alliance from five continents to bring together the best technologies from one country with decision-makers and investors from other countries. Cysmic gave a 90-second pitch about our Erysense technology, which was awarded second place as Best Solutions in #HealthTech and #MedTech.

CES presented a perfect opportunity for Cysmic to get exposure to professionals around the world, establish new business relationships and learn about the latest market trends in the biomedical sector. It is also an opportunity to participate in high-level pitching events and meet experts in different fields.

93rd Annual Meeting of The Society of Rheology

93rd Annual Meeting of The Society of Rheology

The 93rd Annual Meeting of The Society of Rheology (SoR) was held in Chicago, Illinois on October 9-13, 2022. Dr. Steffen M. Recktenwald participated on behalf of Cysmic and presented our latest results in his talk “Microfluidic single-cell shape analysis as a biomarker for pathophysiological red blood cell capillary flow” in the Biomaterials and Biofluid Dynamics session of the meeting. Additionally, his poster “AI-powered single-cell analysis to probe in-vitro capillary blood flow” won first place  (“Best Postdoctoral Fellow Poster Award”) in the poster session, highlighting the interest of the research community in our Cysmic technology including point-of-care devices for blood quality assessment and diagnostics.

Publications

Publications

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Cysmic was born from a group of scientists with a strong background in red blood cell physiology, pathophysiology, biophysics, rare anemias, microfluidics, microscopy, hardware and software development, and AI.
Below is a list of our most recent blood research-related peer-reviewed publications:
  • Recktenwald, S.M., M.G.M. Lopes, S. Peter, S. Hof, G. Simionato, K. Peikert, A. Hermann, A. Danek, K. van Bentum, H. Eichler, C. Wagner, S. Quint, and L. Kaestner. 2022. Erysense, a Lab-on-a-Chip-Based Point-of-Care Device to Evaluate Red Blood Cell Flow Properties With Multiple Clinical Applications. Front. Physiol. 13:1–10. doi: 10.3389/fphys.2022.884690.
  • Recktenwald, S.M., K. Graessel, F.M. Maurer, T. John, S. Gekle, and C. Wagner. 2022. Red blood cell shape transitions and dynamics in time-dependent capillary flows. Biophys. J. 121:23–36. doi: 10.1016/j.bpj.2021.12.009.
  • Minetti, G., A.Y. Bogdanova, H. Mairbäurl, and L. Kaestner. 2022. Space anemia unexplained: Red blood cells seem to be space‐proof. Am. J. Hematol. doi: 10.1002/ajh.26663.
  • Kaestner, L. 2022. Artificial intelligence: Training the trainer. Br. J. Haematol. 1–2. doi: 10.1111/bjh.18358.
  • Rabe, A., A. Kihm, A. Darras, K. Peikert, G. Simionato, A.K. Dasanna, H. Glaß, J. Geisel, S. Quint, A. Danek, C. Wagner, D.A. Fedosov, A. Hermann, and L. Kaestner. 2021. The Erythrocyte Sedimentation Rate and Its Relation to Cell Shape and Rigidity of Red Blood Cells from Chorea-Acanthocytosis Patients in an Off-Label Treatment with Dasatinib. Biomolecules. 11:727. doi: 10.3390/biom11050727.
  • Simionato, G., K. Hinkelmann, R. Chachanidze, P. Bianchi, E. Fermo, R. van Wijk, M. Leonetti, C. Wagner, L. Kaestner, and S. Quint. 2021. Red blood cell phenotyping from 3D confocal images using artificial neural networks. PLOS Comput. Biol. 17:e1008934. doi: 10.1371/journal.pcbi.1008934. doi: 10.1371/journal.pcbi.1008934.
  • Martin-Wortham, J., S.M. Recktenwald, M.G.M. Lopes, L. Kaestner, C. Wagner, and S. Quint. 2021. A deep learning-based concept for high throughput image flow cytometry. Appl. Phys. Lett. 118:123701. doi: 10.1063/5.0037336.
  • Kihm, A., S. Quint, M.W. Laschke, M.D. Menger, T. John, L. Kaestner, and C. Wagner. 2021. Lingering Dynamics in Microvascular Blood Flow. Biophys. J. 120:432–439. doi: 10.1016/j.bpj.2020.12.012.
  • Simionato, G., R. van Wijk, S. Quint, C. Wagner, P. Bianchi, and L. Kaestner. 2021. Rare Anemias: Are Their Names Just Smoke and Mirrors? Front. Physiol. 12:1–5. doi: 10.3389/fphys.2021.690604.
  • Abay, A., S.M. Recktenwald, T. John, L. Kaestner, and C. Wagner. 2020. Cross-sectional focusing of red blood cells in a constricted microfluidic channel. Soft Matter. 16:534–543. doi: 10.1039/C9SM01740B.
  • Huisjes, R., A. Makhro, E. Llaudet-Planas, L. Hertz, P. Petkova-Kirova, L.P. Verhagen, S. Pignatelli, M.A.E. Rab, R.M. Schiffelers, E. Seiler, W.W. van Solinge, J.-Ll.V. Corrons, L. Kaestner, M. Mañú-Pereira, A. Bogdanova, and R. van Wijk. 2020. Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis. Haematologica. 105:338–347. doi: 10.3324/haematol.2018.188151.
  • Mahkro, A., I. Hegemann, E. Seiler, G. Simionato, V. Claveria, N. Bogdanov, C. Sasselli, P. Torgerson, L. Kaestner, M.G. Manz, J.S. Goede, M. Gassmann, and A. Bogdanova. 2020. A pilot clinical phase II trial MemSID: Acute and durable changes of red blood cells of sickle cell disease patients on memantine treatment. eJHaem. 1:23–34.  doi: 10.1002/jha2.11.
  • Bogdanova, A., L. Kaestner, G. Simionato, A. Wickrema, and A. Makhro. 2020. Heterogeneity of Red Blood Cells: Causes and Consequences. Front. Physiol. 11:1–11. doi: 10.3389/fphys.2020.00392.
  • Abay, A., G. Simionato, R. Chachanidze, A. Bogdanova, L. Hertz, P. Bianchi, E. van den Akker, M. von Lindern, M. Leonetti, G. Minetti, C. Wagner, and L. Kaestner. 2019. Glutaraldehyde – A Subtle Tool in the Investigation of Healthy and Pathologic Red Blood Cells. Front. Physiol. 10:1–14. doi: 10.3389/fphys.2019.00514.
  • Petkova-Kirova, P., L. Hertz, J. Danielczok, R. Huisjes, A. Makhro, A. Bogdanova, M. del M. Mañú-Pereira, J.-L. Vives Corrons, R. van Wijk, and L. Kaestner. 2019. Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias. Front. Physiol. 10:1–17. doi: 10.3389/fphys.2019.00386.
  • Bernhardt, I., M. C. Wesseling, D.B. Nguyen, and L. Kaestner. 2019. Red Blood Cells Actively Contribute to Blood Coagulation and Thrombus Formation. In: Erythrocyte. IntechOpen. doi: 10.5772/intechopen.86152.
  • Quint, S., A.F. Christ, A. Guckenberger, S. Himbert, L. Kaestner, S. Gekle, and C. Wagner. 2017. 3D tomography of cells in micro-channels. Appl. Phys. Lett. 111:1–5. doi: 10.1063/1.4986392.

    Kontakt

    +49 176 3078 4328

    stephan.quint@cysmic.de

    Cysmic GmbH
    Auf der Trift 1
    66127 Saarbrücken

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    Beyond Science…

    Beyond Science…

    Cysmic established a collaboration with the Saar University of Fine Arts (Hochschule der Bildenden Künste Saar). Based on our microscopy images, we aimed at creating visual art concepts with the scope of sensitizing people to donate blood. Art students proposed original advertising ideas, such as hanging 3D cell models, artistic installations and sculptures of cells, animations to be projected on street screens, plasters with red blood cell emojis, and plate sets with red blood cell patterns. Such creations were presented at an official event in our office. We thank Prof. Gabriele Langendorf, Markus Spang, and Hannes Käfer for their collaboration in this interdisciplinary project.

    Meeting of the European Red Cell Society

    Meeting of the European Red Cell Society

    The 24th meeting of the European Red Cell Society (ERCS) “The horizons in red cell research,” was held from April 7-11, 2022 in Gazzada Schiano (Varese, Italy) at the historic Villa Cagnola. The conference focused on new studies, scientific discoveries, and molecular bases of red cell diseases bringing together authoritative scientists from around the world.
    Cysmic was one of the sponsors of the ERCS meeting and presented the latest technologies applied to the study of red blood cells and membranes. Cysmic CEO Dr. Stephan Quint introduced the Erysense technology in his talk “Erysense: An automated point-of-care device for blood quality assessment”. Dr. Greta Simionato further highlighted the potential of Erysense for therapy monitoring in her presentation “Red blood cells influence blood flow and plasma content in severe COVID-19”. The meeting also featured a poster session and Cysmic Ph.D. student Marcelle Lopes won the award for the best scientific poster presentation – congratulations!